After a neurological event, patients require a fast, accurate, and objective measurement of their pupillary light reflex. Quantitative pupillometry has its own CPT code to help you collect this measurement accurately and bill accordingly. This measurement matters in neurology, ophthalmology, and acute settings, and today’s tools make this data even more valuable. Using CPT code 95919 with Virtual Field, you can collect consistent results that support diagnosis, monitoring, and reimbursement.

Summary

• CPT 95919 is a newer code that covers quantitative pupillometry, or automated measurement of pupil response.
• It replaces subjective penlight testing with reproducible metrics for clinical decision-making.
• This test is reimbursable by Medicare and commercial payors when medically necessary, and Virtual Field makes this test exceptionally efficient.

What This Code Covers

The American Medical Association defines CPT^® 95919 as:

“Quantitative pupillometry with physician or other qualified health care professional interpretation and report, unilateral or bilateral."

95919 is a newer CPT code. From 2014 to 2021, quantitative pupillometry was reported under 0341T, then in 2022 it was moved to CPT 92499: “unlisted ophthalmological services or procedure.” In the 2023 code set, quantitative pupillometry was finally defined under CPT code 95919. This upgrade shows the importance of neurological exams in eye care and underscores the advances made in quantitative pupillometry.

Historically, pupillometry was done using a penlight, and it wasn’t easily quantifiable. Today, automated pupillometry devices can measure pupil size and symmetry, response to light, constriction, dilation, and recovery time. All of these details can be highly revealing to a patient’s neurological health.

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When and Why to Use CPT 95919 with Virtual Field

Quantitative pupillometry is particularly valuable when pupil function may reveal or track disease, or following a traumatic brain injury (TBI). Unlike the classic penlight test, automated pupillometry measures the pupillary reflex in millimeters and milliseconds. This supports tracking a patient’s neurologic status and provides defensible documentation for reimbursement.

CPT 95919 can be used for both acute and ongoing monitoring:

• Neuro-ophthalmology assessments (anisocoria, optic neuropathies)
• Post-stroke or traumatic brain injury follow-up
• ICU/critical care monitoring of neurologic function
• Preoperative LASIK evaluation

Virtual Field integrates pupillometry testing seamlessly into the same headset used for visual field exams. It’s now possible to complete a wide range of ophthalmological exams all in one portable device.

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Eligibility and Clinical Indications

In an acute setting, CPT 95919 would be relevant to a patient who has experienced a TBI or stroke. After the incident, more pupillometry exams may help measure the recovery process.

For diagnostic and long-term condition monitoring, CPT 95919 could be helpful for patients with neurodegenerative diseases like Parkinson’s disease or multiple sclerosis. Rare eye conditions like Horner’s syndrome or Adie’s pupil can be accurately measured with precise pupillometry. A traditional penlight test couldn’t provide the same level of detail.

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Documentation Checklist

With CPT 95919, you can bill for what was once an ad-hoc, undocumented exam. The level of detail achievable with quantitative pupillometry can improve patient care, but proper documentation supports defensibility. Although the pupillometry CPT code 95919 sits in the neurology/autonomic testing family, ophthalmologists can bill it when pupillometry is clinically indicated and documented.

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CPT 95919 Documentation Checklist

• Reason for testing
• Patient history (brief ocular or systemic relevant history)
• Pupillometry test results (automated output)
• Interpretation statement by the ophthalmologist or optometrist
• Signed report stored in the patient's chart

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Step-by-Step Billing Workflow

Follow these simple steps to conduct the 95919 correctly and bill appropriately.

Step 1: Order the Test

Identify the indication for testing. This could be a neurologic event, trauma, abnormal pupils, or monitoring a patient with a known neurological condition.

Step 2: Technician Performance

Perform an automated pupillometry test with a digital pupillometer or Virtual Field’s VF3 Pro. Virtual Field’s VR pupil test collects consistent and reproducible results when it records the pupil’s response to a stimulus.

Step 3: Physician Interpretation

Review the test results, document your interpretation, and confirm the report. Don’t forget to sign the report in the patient’s chart and store it securely.

Step 4: Claim Submission

Submit the claim using CPT 95919. Include any modifiers and the linked ICD-10 diagnosis code.

Relevant modifiers include:

• -26: Professional Component
• -TC: Technical Component

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Reimbursement Snapshot

The national average fee and RVUs (relative value units) for CPT 95919 are set by CMS (the Centers for Medicare & Medicaid Services) and are maintained in the Medicare Physician Fee Schedule (MPFS). These numbers can vary by region and by payor, so check for updates annually.

As of September 2025, the global period is zero days, meaning there are no bundled post-care limitations. Depending on your location, setting, and modifiers, CPT code 95919 is currently reimbursable between $15 and $20. The current wRVU per unit is 0.18.

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Common Denial Reasons and How to Avoid Them

Claims denials are possible, and some payors may not cover CPT 95919 at all. Check all claims details and documentation to increase the likelihood of coverage.

Lack of Medical Necessity

Claims are often denied if the documentation is missing or doesn’t sufficiently support that autonomic function testing is medically necessary for diagnosis or treatment.

Missing or Incorrect Modifiers

Pupillometry reimbursement denials happen when required modifiers are missing or incorrectly applied to the procedure code. Always check for complete documentation and review modifiers before submission.

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‍Bringing Pupillometry Into Your Workflow

About 2.8 million Americans sustain a TBI every year, and more than half of them will experience some form of visual dysfunction. Using quantitative pupillometry under CPT 95919 gives you a minimally invasive, fast, and precise way to measure vital signs and track progress. When you’re using Virtual Field for comprehensive vision testing, you can now include pupillometry to support more neurological patients.

If you haven’t tried pupillometry on your Virtual Field yet, schedule a demo today to see how it can integrate into your workflow.